Novel Magnetic Resonance Imaging-Guided Ultrasound-Stimulated Microbubble Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer

The IEEE Magnetics Toronto Section invites you to a seminar exploring advancements in cancer treatment through the application of ultrasound-stimulated microbubbles (USMB) to enhance external beam radiotherapy. Previous studies have demonstrated that USMBs can amplify radiotherapy effects by up to 40-fold, offering significant promise for improving therapeutic outcomes. This presentation will focus on an ongoing phase I clinical trial investigating USMBs as an adjunct to fractionated radiation therapy in patients with locally advanced breast cancer and inoperable tumors near the chest wall. Central to the trial is the Symphony MRI-guided FUS system, a pioneering technology developed by Arrayus Technologies. This system integrates: – A large-aperture, densely populated phased array for fully electronic beam steering. – Advanced MRI-guided spatial targeting with finely adjustable treatment contouring. – Real-time magnetic resonance thermometry for precise monitoring and control. Speaker(s): David Alberico Room: KHS369, Bldg: Kerr Hall South, Toronto Metropolitan University, 350 Victoria Steet, Toronto, Ontario, Canada, M5B2K3